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Article discusses whether treatment is effective and concludes that there is no evidence of risk reduction of late miscarriage or spontaneous very preterm birth. The author therefore suggests that use of antibiotics to prevent preterm delivery in this patient population should be reconsidered.

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References

  1. D. Subtil, G. Brabant, E. Tilloy, P. Devos, F. Canis, A. Fruchart, M. Bissinger, J. Dugimont, C. Nolf, C. Hacot, S. Gautier, J. Chantrel, M. Jousse, D. Desseauve, J.L. Plennevaux, C. Delaeter, S. Deghilage, A. Personne, E. Joyez, E. Guinard, E. Kipnis, K. Faure, B. Grandbastien, P. Ancel, F. Goffinet, and R. Dessein, "Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial", The Lancet, vol. 392, pp. 2171-2179, 2018. http://dx.doi.org/10.1016/S0140-6736(18)31617-9