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MecA expressed by Staphylococcus causes resistance to oxacillin/methicillin resulting in methicillin-resistant Staphylococcus aureus (MRSA). This happens when isolates produce an altered penicillin-binding protein, PBP2a, encoded by the mecA gene. The following article discusses MRSA and what antibiotics are ineffective.

  1. https://www.cdc.gov/mrsa/lab/index.html. https://www.cdc.gov/mrsa/lab/index.html. https://www.cdc.gov/mrsa/lab/index.html

https://www.cdc.gov/mrsa/lab/index.html